Drug slows Alzheimer's but can it make a real difference?

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Drug slows Alzheimer's but can it make a real difference?
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New data shows an experimental Alzheimer's drug modestly slowed the brain disease's inevitable worsening.

FILE - This Oct. 7, 2003 file photo shows a closeup of a human brain affected by Alzheimer's disease, on display at the Museum of Neuroanatomy at the University at Buffalo in Buffalo, N.Y. An experimental Alzheimers drug modestly slowed the brain diseases inevitable worsening, researchers reported Tuesday, Nov. 29, 2022 - and the next question is how much difference that might make in peoples lives. Japanese drugmaker Eisai and its U.S.

Every two weeks for 18 months, study participants received intravenous lecanemab or a dummy infusion. Researchers tracked them using an 18-point scale that measures cognitive and functional ability. “It is unlikely that the small difference reported in this trial will be noticeable by individual patients,” said Dr. Madhav Thambisetty of the National Institute on Aging, who noted he wasn’t speaking for the government agency.

behind Alzheimer’s -- can delay disease progression, said Maria Carrillo, chief science officer for the Alzheimer’s Association. Amyloid-targeting drugs can cause side effects that include swelling and bleeding in the brain, and lecanemab did as well. One type of this swelling was seen in about 13% of recipients. Eisai said most were mild or asymptomatic.

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