If regulators approve it, the drug could become the first new medicine for Alzheimer's patients in nearly two decades.
SAN DIEGO — A drug that curbs delusions in Parkinson's patients did the same for people with Alzheimer's disease and other forms of dementia in a study that was stopped early because the benefit seemed clear.
It targets some of the most troubling symptoms that patients and caregivers face — hallucinations that often lead to anxiety, aggression, and physical and verbal abuse."This would be a very important advance," said one independent expert, Dr. Howard Fillit, chief science officer of the Alzheimer’s Drug Discovery Foundation.
Although the field is focused on finding a cure for dementia and preventing future cases,"there is a huge unmet need for better treatment" for those who have it now, said Maria Carrillo, the Alzheimer's Association's chief science officer. The drug is pimavanserin, a daily pill sold as Nuplazid by Acadia Pharmaceuticals Inc. It was approved for Parkinson's-related psychosis in 2016 and is thought to work by blocking a brain chemical that seems to spur delusions.Sign Up
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