Donor's Immune Cells Help Transplant Recipients

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Donor's Immune Cells Help Transplant Recipients
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A liver transplant can give people a new lease on life, but at the cost of lifelong immune-suppressing medication and its risks. Now an innovative approach to reduce, or possibly eliminate, certain patients' reliance on those drugs is showing early promise. The tactic is...

A liver transplant can give people a new lease on life, but at the cost of lifelong immune-suppressing medication and its risks. Now an innovative approach to reduce, or possibly eliminate, certain patients' reliance on those drugs is showing early promise.

The findings, published Oct. 11 in the journal Science Translational Medicine, are "encouraging," according to an expert not involved in the research. "The immune system is complex and may be stimulated by other events besides just the transplanted organ," said Sonnenday, who is also a member of the American Liver Foundation's transplant work group.

In the new study, Thomson and his colleagues wanted to see if, ahead of such a transplant, they could set up a friendlier immune system environment for the donor liver.

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