Infections of ancestors lying dormant in DNA can be activated to help immune system attack tumours
Remnants of ancient viruses passed down over thousands or even millions of years in human DNA could help fight cancer, a study has found.
Julian Downward, the associate research director and head of the oncogene biology laboratory at the institute, said: “This work opens up a number of new opportunities for improving patient responses to immunotherapy, a crucial step in helping more people survive lung cancer.” In the majority of healthy tissue these viral genes are silenced, but in cancers they can be woken up.
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