Treatment of primary progressive MS with DMTs for patients experiencing relapse or with disease activity is linked to a significant reduction of long-term disability risk, new research shows.
While a variety of DMTs are approved for the treatment of relapsing-remitting MS , randomized trials have generally not shown similar benefits among patients with PPMS ― which is why only ocrelizumab is currently approved for the indication.
The key characteristics associated with reaching the 7.0 or higher EDSS score included having a higher EDSS score at baseline , having relapses , and treatment with DMTs . While the link between relapse activity and improved outcomes may appear counterintuitive, such activity in patients who are receiving a DMT"cannot be compared with that occurring without treatment," the investigators note.
"Therefore, it would be crucial to identify, at the time of treatment introduction, patients who may experience persistent inflammatory activity in order to maximize the benefit-risk balance," they add.
Malaysia Latest News, Malaysia Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
2022 Subaru Outback Wilderness long-term review, Part 2 | Car News | Auto123Auto123 puts the 2022 Subaru Outback Wilderness 2022 to the long-term test. Today, part 2, in which we poke around the Wilderness beneath all the badging.
Read more »
2022 BMW 330e Long-Term Update | Locking upThere are three things that drive us nuts about our long-term 2022 BMW 330e when it comes time to end the drive.
Read more »
Choco Taco may make a return, Klondike saysThe ice cream manufacturer says an outpouring of support for the product has made them “reconsider our long-term plans.”
Read more »
Galaxy Z Fold 3 Long-term durability report: Here’s what Samsung still can’t get right | EngadgetSamsung has made a lot of improvements to the durability of its foldable phones, but one big issue remains.
Read more »
Long-term mortgage rates under 5% for 1st time in 4 monthsThe average long-term U.S. mortgage rate fell below 5% for the first time in four months, days after the Federal Reserve jacked up its main borrowing rate in an aggressive effort to get inflation under control.
Read more »
Keeping D.J. Humphries In Arizona Long-Term A Smart MoveThe Arizona Cardinals signed offensive tackle D.J. Humphries to a three-year contract extension worth $66.8 million on Tuesday evening.
Read more »