The virtual replica of a condition simulates the disease's progress, helping doctors make decisions.
Associate Professors Bee Yong Mong and Rinkoo Dalan worked on the project using HealthVector Diabetes to predict the risk of CKD onset in diabetes patients over three years.
According to the 2023 annual report by the US Renal Data System, Brunei in 2021 topped the list of countries with the highest rates of CKD due to diabetes, with 370 per million population . “When you look at Stage 5 or end-stage kidney failure among all the dialysis patients, about 70 per cent have diabetes as the underlying contributing factor.“In terms of the trend from 2010 to 2019, we see a large increase in the prevalence of end-stage kidney disease. I think part of this is because our diabetes patients are surviving longer with better treatments,” he added.
The metabolic digital twin software uses data analysis and artificial intelligence to predict the risk of CKD onset in diabetes patients over three years. Using information such as fasting blood sugar levels, cholesterol measurements, body mass index and blood pressure, the software estimates the three-year risk for CKD development in Type 2 diabetes patients who do not have pre-existing kidney issues.
“, we developed this algorithm further and subsequently fine-tuned and validated it by adding the SingHealth diabetes registry,” Prof Bee said.
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