Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring - Nature Medicine

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Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring - Nature Medicine
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Longitudinal study of plasma biomarkers, in 2 independent cohorts, highlighted only p-tau217 as a surrogate marker of disease progression in early Alzheimers disease Biofinder_study OskarHansson9 NicholasAshton

This work was supported by the European Union’s Horizon 2020 research and innovation program to E.V.M. and H.Z.), the Swedish Research Council and 2017-00915 to K.B.

Nicholas J. Ashton, Wagner S. Brum, Thomas K. Karikari, Fernándo González-Ortiz, Guglielmo Di Molfetta, Francisco J. Meda, Henrik Zetterberg & Kaj Blennow King’s College London, Institute of Psychiatry, Psychology and Neuroscience, Maurice Wohl Institute Clinical Neuroscience Institute, London, UKNIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia at South London and Maudsley NHS Foundation, London, UKCentre for Age-Related Medicine, Stavanger University Hospital, Stavanger, NorwayClinical Memory Research Unit, Faculty of Medicine, Lund University, Lund,...

Shorena Janelidze, Niklas Mattsson-Carlgren, Alexa Pichet Binette, Olof Strandberg, Sebastian Palmqvist, Erik Stomrud & Oskar HanssonNiklas Mattsson-CarlgrenGraduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul , Porto Alegre, BrazilThomas K. Karikari Wisconsin Alzheimer’s Institute, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USAWisconsin Alzheimer’s Disease Research Center, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USADepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USASILQ Center, Washington University School of Medicine, St.

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