The cause of the blast is not yet known.
Ambulances rushed to the scene on the packed Istiklal Avenue, which police quickly cordoned off. The area, in the city's Beyoglu district, had been crowded as usual with shoppers, tourists and families, TRT and other media reported."There was a loss of life and injuries," Istanbul Governor Ali Yerlikaya said on Twitter, adding that the explosion occurred around 4.20 p.m. local time .
Turkey's RTUK regulator imposed a broadcast ban on coverage of the blast around an hour after it occurred.
Malaysia Latest News, Malaysia Headlines
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