Viral levels resurge in more than 10% of untreated people with COVID-19, but early data hint that the rebound is even more pronounced after antiviral treatment.
The Pfizer trial team noticed cases of rebound both in people who got Paxlovid and in those who took a placeboTo determine the frequency of rebound in the absence of Paxlovid treatment, Jonathan Li, a physician-scientist at Brigham and Women’s Hospital in Boston, Massachusetts, and his team analysed data from hundreds of people who were randomized to receive a placebo in a large-scale trial of COVID-19 antibody drugs.
. Yet, just 1–2% of people had both features of rebound. The study was posted to the medRxiv preprint server on 2 August and has not yet been peer reviewed.Li says that this suggests that the rebound of SARS-CoV-2 rarely causes symptoms, and that symptoms’ reappearance could stem instead from factors other than viral resurgence, such as lingering immune responses or another infection altogether.
Charness says that Paxlovid rebound does seem to be qualitatively different from rebound in untreated people, whose viral levels rarely reached the peaks of their initial infection.But the cause of Paxlovid rebound remains unclear. Studies have suggested that it’s unlikely to be due to viral drug resistance or feeble immune responses in rebounders.
Malaysia Latest News, Malaysia Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Overnight restrictions planned on north- andsouthbound Interstate 19 in Sahuarita Thursday, Aug. 10
Read more »
World Health Organization: COVID-19 Deaths Fall Overall by 9%, Infections StableThe U.N. health agency said there were more than 14,000 COVID-19 deaths in the last week and nearly 7 million new infections. The number of new deaths rose by 19% in the Middle East, while dropping by more than 70% in Africa, 15% in Europe and 10% in the Americas.
Read more »
Deepwater Horizon Oil Spill Still Detectable 10 Years Later, Scientists SayThe Deepwater Horizon oil spill was not a short-lived catastrophe. Over 10 years after one of the largest environmental disasters in human history, a sticky oil residue still coats some marshland in the Gulf of Mexico, a new report reveals. Its imp
Read more »
10 Expert-Approved Products to Revive Sunburned SkinSunburn has met its match.
Read more »
These Are the Top 10 Best States to Have a Baby In 2022Read about a survey from WalletHub that looked at the best states to have a baby in based on cost, health care access, baby-friendliess and family friendliness.
Read more »
10 Years Later, Bugatti's Veyron 16.4 Grand Sport Vitesse Remains The World's Fastest Roadster | Carscoops10 Years Later, Bugatti's Veyron 16.4 Grand Sport Vitesse Remains The World's Fastest Roadster | Carscoops carscoops
Read more »