Findings may aid design of targeted drug delivery into the brain and central nervous system. Researchers have developed a zebrafish model to study omega-3 fatty acid transport into the brain, offering insights into lipid transport across the blood-brain barrier and potential drug delivery optimiz
Step-by-step process of lipid transport across blood-brain barrier. Credit: Image created by Ethan Tyler from NIH Medical ArtsResearchers have developed a zebrafish model to study omega-3 fattytransport into the brain, offering insights into lipid transport across the blood-brain barrier and potential drug delivery optimization.
Researchers at the University of California, Los Angeles David Geffen School of Medicine, the Howard Hughes Medical Institute at UCLA, and the have developed a zebrafish model that provides new insight into how the brain acquires essential omega-3 fatty acids, including docosahexaenoic acid , regulate important cellular functions.
Reference: “Lipid flipping in the omega-3 fatty-acid transporter” by Chi Nguyen, Hsiang-Ting Lei, Louis Tung Faat Lai, Marc J Gallenito, Xuelang Mu, Doreen Matthies and Tamir Gonen, 8 May 2023,
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