Longitudinal neuroimaging before and after infection by SARS-CoV-2.
. Each IDP conveys different information — the volume or microstructural tissue properties of distinct brain structures, for instance, or the strength of neural connectivity between pairs of brain regions. More than 2,000 IDPs are generated for each person from each scan session. In addition, Douauddeveloped a set of IDPs to test the hypothesis that areas of the brain involved in taste and smell would be altered, given that these senses are often impaired in COVID-19.
It is surprising that Douaud and colleagues identified these brain changes, given that most people in the case group experienced mild to moderate symptoms of COVID-19. Even when the authors excluded from their analysis the small number of people who required hospitalization, the results did not change.
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