WASHINGTON, May 2 ― Commonly used blood pressure medicines do not heighten susceptibility to Covid-19 infection, or increase the risk of becoming seriously ill with the disease, three major studies said yesterday, positive news for the millions of people who take them. The research primarily...
Saturday, 02 May 2020 11:12 AM MYT
The research primarily concerned angiotensin-converting–enzyme inhibitors and angiotensin-receptor blockers , which are also given to diabetes patients to help protect their kidneys. Confusing matters further, there were also contradictory animal studies that showed having more ACE2 proteins might lessen an inflammatory reaction in lungs to Covid-19, a beneficial effect.Each involved reviewing the records of thousands of people either on or not on the medicines and seeing if they got infected and how the disease progressed.
The authors of an accompanying editorial in the NEJM acknowledged this inherent limitation, but added: “We find it reassuring that three studies in different populations and with different designs arrive at the consistent message.” This is especially important given that lockdown life itself appears to be causing high blood pressure, “maybe from stress or less exercise or eating differently,” she added.
“The same drugs that appear to have life saving benefits in patients with cardiovascular illness also appear to show us a signal of benefit in patients who are in the throes of Covid-19,” he said.
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