Researchers have demonstrated that biological aging can accelerate under stress but also decelerate when stressors are removed, using a mouse model and human stress cohorts. This fluidity of aging raises questions about the triggers of aging speed, including the potential impact of mental health iss
Products have flooded the marketplace that purport to make a person appear younger. Anti-aging creams and serums line store shelves, and if that’s not enough, there’s always Botox or facelifts, liposuction, cool sculpting, or implants.
The team looked at the liver, heart, brain, kidney, and fat tissues of the mouse models two months after completing parabiosis, and using a variety of DNA methylation clocks, determined that all young mice aged faster when exposed to old blood and reversed back to baseline age after separation and recovery.
Obviously, it’s not exactly natural to be surgically attached via blood vessels to another living creature, so the team wondered whether the same fluctuation in biological aging could be true without sharing old blood. This held true for patients needing emergency surgical repair for a traumatic hip fracture. Blood samples were taken before surgery, one day after surgery, and before patients were discharged from the hospital. The team found a significant increase in biological age markers in the first 24 hours of hospital admittance, but by the time they were discharged, patients’ biological ages dropped, even though many of these patients were in their 70s and 80s.
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