Researchers have identified a biochemical marker in the blood that could help identify newborn babies at risk for sudden infant death syndrome.
The researchers, in a study published in The Lancet’s eBio Medicine https://www.sciencedirect.com/science/article/pii/S2352396422002225, found that babies who died of SIDS had lower levels of an enzyme called butyrylcholinesterase shortly after birth. BChE plays a major role in the brain’s arousal pathway, and low levels would reduce a sleeping infant’s ability to wake up or respond to its environment.
But researchers are “only halfway” to the goal of fully understanding SIDS and being able to prevent it, other experts said on Saturday in The New England Journal of Medicine https://www.nejm.org/doi/full/10.1056/NEJMp2119221 . Using dried blood spots taken at birth as part of a newborn screening program, the researchers compared BChE levels in 26 babies who later died of SIDS, 41 infants who died of other causes, and 655 surviving infants.
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