Androgen receptor activity in T cells limits checkpoint blockade efficacy - Nature

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Androgen receptor activity in T cells limits checkpoint blockade efficacy - Nature
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A Nature research paper explores how androgen signaling in T cells can influence immunotherapy responses in prostate cancer

Present address: Bristol Myers Squibb, New Brunswick, NJ, USAThese authors jointly supervised this work: Zheng Xia, Amy E.

Fanny Polesso, Chaojie Wang, Archana Sehrawat, Reed M. Hawkins, Breanna Caruso, Christina Hipfinger & Amy E. MoranKnight Cancer Institute, Oregon Health and Science University, Portland, OR, USADepartment of Pathology and Laboratory Medicine, Oregon Health and Science University, Portland, OR, USADepartment of Radiation Medicine, Oregon Health and Science University, Portland, OR, USAReid F. Thompson, Mary A. Wood & Julie N.

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