Boston medical researchers are hoping to get ahead of Alzheimer’s by testing a possible treatment in patients who don’t have symptoms but may be at risk for the progressive disease.
Brigham and Women’s Hospital is part of the global AHEAD Study, an Alzheimer’s clinical trial that is looking at whether an investigational treatment can slow or stop the earliest brain changes in people with a higher risk of developing the disease later in life.
“My hope is we find a treatment, coupled with lifestyle, that prevents the onset of Alzheimer’s disease for people who might have a higher risk,” added Gale, a neurologist who’s co-director of the Brain Health Program in the Division of Cognitive and Behavioral Neurology. In the AHEAD study, the researchers are testing the effect of lecanemab in healthy people who have amyloid in their brain, known as preclinical Alzheimer’s disease.
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