American Cancer Society study reinforces link between routine PSA testing and catching early-stage disease.
Cases of advanced prostate cancer have increased among American men ages 50 and older, while cases of early-stage disease have declined, a study published Wednesday found.
Each year in the United States, there are about 192,000 new cases of prostate cancer and 33,000 deaths. Thankfully, most cases are slow-growing and not life-threatening. Many cases can take a decade or more to show symptoms, if at all, and may never be fatal. Jemal said other risk factors for advanced prostate cancer, such as family history of the disease or obesity, probably can’t explain the increases seen in his study.
By comparison, the incidence of advanced cancers that had spread beyond the prostate gland — known as regional-stage or distant-stage cancers — increased at “an alarming rate,” Jemal told NBC News. Jemal said he hopes current federal screening recommendations will prompt men to talk with their doctors about the pros and cons of PSA screening so more aggressive cancers may be caught. “There has to be a balance,” he said.
Though the explanation is unclear and could potentially include environmental, lifestyle or other factors, he said he believes the changing screening guidelines were a driving factor. “When you relax screening, these are the downstream effects,” he said. “There are more cancers that show up in a more advanced stage.”
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