Researchers from the University of Auckland have discovered that new combinations and formulations of older medicines are promising for the treatment of bowel cancer. According to a team of University of Auckland scientists, the use of old drugs in new combinations is showing potential in the tre
The researchers think that pyrvinium, a cheap drug created in the 1960s could be modified for use in the treatment of cancer.
“While there have been advances in treatments for this disease in recent years, the development of new medicines is expensive and time-consuming,” lead researcher Professor Peter Shepherd says. “As a possible solution to this problem, our group has been investigating whether using old drugs in new ways could provide a faster and cheaper way of treating this disease.”
“In recent years, research has led to a rapid increase in our understanding of how colorectal cancer develops. In particular, some subtypes of the disease rely on the development of small blood vessels and on proteins called BRAF and beta-catenin. The research group identified existing drugs that target these and investigated the possibility that combining them could have powerful anti-cancer effects.
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