Texans rookie wide receiver John Metchie III likely miss the 2022 season as he recovers...
Acute promyelocytic leukemia is an aggressive form of blood cancer. It occurs in people whose body does not produce enough normal blood cells and platelets. As a result, immature blood cells build up in the person's bone marrow, the spongy interior of bones.
Over time, those diagnosed with the rare cancer face an increased risk of life-threatening blood clots. They also may experience dangerous bleeding after minor injuries -- especially dangerous for anyone who, like Metchie, gets pummeled for a living. Doctors are improving at distinguishing acute promyelocytic leukemia from other types of blood cancer. Cancer researchers believe the rare disease is caused by a genetic change in a person's chromosomes that develops after infancy.For those diagnosed with acute promyelocytic leukemia, the warning signals can seem benign at first. According to the National Institutes of Health, the most common symptoms are mysterious bruises, loss of appetite, anemia and excessive bleeding.
Some people may also experience nosebleeds and have trouble breathing. Less common symptoms include bone and abdominal pain. But because these symptoms can be related to many different diseases, including other blood cancers, acute promyelocytic leukemia can be hard to diagnose. Without firsthand experience, doctors may not immediately recognize the signs, according to the NIH.On average, doctors diagnose between 600 and 800 cases of the rare leukemia annually, according to the National Organization for Rare Diseases.
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